Britta Engelhardt Selected Research

7a- (4- (heptyloxy)phenethyl)tetrahydro- 1H- oxazolo(3,4- c)oxazole

10/2014

Novel oxazolo-oxazole derivatives of FTY720 reduce endothelial cell permeability, immune cell chemotaxis and symptoms of experimental autoimmune encephalomyelitis in mice.

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Britta Engelhardt Research Topics

Disease

32	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2021 - 02/2002
28	Multiple Sclerosis 11/2022 - 02/2002
20	Inflammation (Inflammations) 01/2021 - 08/2002
10	Neuroinflammatory Diseases 11/2022 - 01/2017
6	Stroke (Strokes) 12/2018 - 01/2008
5	Autoimmune Diseases (Autoimmune Disease) 09/2020 - 02/2002
5	Relapsing-Remitting Multiple Sclerosis 01/2016 - 01/2008
3	Infections 12/2020 - 09/2011
3	Encephalomyelitis (Myeloencephalitis) 09/2020 - 12/2015
3	Edema (Dropsy) 11/2012 - 11/2004
2	Nervous System Diseases (Neurological Disorders) 01/2019 - 01/2008
2	Ischemic Stroke 12/2018 - 01/2018
2	Brain Ischemia (Cerebral Ischemia) 12/2018 - 11/2012
2	Reperfusion Injury 01/2018 - 03/2013
2	Brain Neoplasms (Brain Tumor) 11/2014 - 05/2002
2	Ischemia 03/2013 - 11/2012
2	Alzheimer Disease (Alzheimer's Disease) 09/2011 - 01/2008
2	Crohn Disease (Crohn's Disease) 01/2008 - 08/2005
2	Progressive Multifocal Leukoencephalopathy 01/2008 - 08/2005
2	Neoplasms (Cancer) 03/2006 - 03/2005
1	Mitochondrial Diseases (Mitochondrial Disease) 11/2022
1	Disease Progression 04/2021
1	Narcolepsy 01/2021
1	Cognitive Dysfunction 01/2021
1	Enteritis 01/2020
1	Critical Illness (Critically Ill) 01/2020
1	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 12/2018
1	Arthritis (Polyarthritis) 01/2018
1	Atherosclerosis 01/2018
1	Necrosis 01/2018
1	Hemorrhage 01/2017
1	Central Nervous System Diseases (CNS Diseases) 01/2014

Drug/Important Bio-Agent (IBA)

10	IntegrinsIBA 01/2020 - 01/2003
9	Pharmaceutical PreparationsIBA 01/2021 - 07/2003
7	LigandsIBA 09/2020 - 06/2003
6	Natalizumab (Tysabri)FDA Link 03/2011 - 08/2005
5	Fingolimod Hydrochloride (FTY720)FDA Link 01/2021 - 10/2014
5	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2019 - 11/2003
4	ChemokinesIBA 01/2022 - 08/2002
4	Proteins (Proteins, Gene)FDA Link 11/2014 - 01/2005
4	P-SelectinIBA 03/2011 - 06/2003
3	CytokinesIBA 12/2020 - 07/2008
3	AntigensIBA 09/2020 - 03/2011
3	Platelet Endothelial Cell Adhesion Molecule-1IBA 01/2019 - 02/2002
3	Claudin-3IBA 01/2019 - 06/2003
3	Glycoproteins (Glycoprotein)IBA 03/2011 - 06/2003
2	Therapeutic UsesIBA 01/2022 - 01/2008
2	Neuroprotective AgentsIBA 01/2022 - 03/2011
2	Junctional Adhesion MoleculesIBA 10/2018 - 01/2012
2	Peptide Hydrolases (Proteases)FDA Link 01/2018 - 03/2013
2	Activated-Leukocyte Cell Adhesion Molecule (Neurolin)IBA 08/2017 - 01/2017
2	7a- (4- octylphenethyl)tetrahydro- 1H- oxazolo(3,4- c)oxazoleIBA 01/2016 - 10/2014
2	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 12/2015 - 10/2007
2	AgrinIBA 11/2014 - 11/2012
2	Estrogen ReceptorsIBA 09/2011 - 12/2010
2	Estrogens (Estrogen)FDA Link 09/2011 - 12/2010
2	Monoclonal AntibodiesIBA 02/2009 - 01/2008
2	AntibodiesIBA 08/2005 - 11/2004
1	Oxidants (Oxidizing Agents)IBA 11/2022
1	Biological ProductsIBA 01/2022
1	Vitamin D FDA LinkGeneric 01/2022
1	EndocannabinoidsIBA 04/2021
1	Sphingosine-1-Phosphate ReceptorsIBA 01/2021
1	Histamine H3 Receptors (Histamine H3 Receptor)IBA 01/2021
1	Histamine (Histamine Dihydrochloride)FDA Link 01/2021
1	pitolisantIBA 01/2021
1	Histone Deacetylase 1IBA 01/2021
1	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2021
1	lipoxin A4IBA 01/2021
1	LipidsIBA 01/2021
1	piperidineIBA 01/2021
1	siponimodIBA 09/2020
1	MorpholinosIBA 09/2020
1	teriflunomideIBA 01/2020
1	Adenosine Triphosphate (ATP)IBA 01/2020
1	Cladribine FDA LinkGeneric 01/2020
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2020
1	Mitoxantrone (Novantrone)FDA LinkGeneric 01/2020
1	Angiopoietin-2IBA 01/2020
1	Virulence Factors (Pathogenicity Factors)IBA 01/2020
1	TIE-2 Receptor (Receptor, TIE 2)IBA 01/2020
1	Dextrans (Dextran)FDA Link 11/2019
1	Chemokine CXCL12IBA 11/2019
1	ClaudinsIBA 09/2019
1	SmokeIBA 03/2019
1	AcidsIBA 01/2019
1	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 01/2019
1	Cell Adhesion MoleculesIBA 12/2018
1	Excitatory Amino AcidsIBA 01/2018
1	AlarminsIBA 01/2018
1	Etanercept (Enbrel)FDA Link 01/2018
1	CC ChemokinesIBA 01/2018
1	P-selectin ligand proteinIBA 01/2017
1	Myelin-Oligodendrocyte GlycoproteinIBA 01/2017
1	sphingosine kinaseIBA 01/2016
1	Tissue Plasminogen Activator (Alteplase)FDA Link 01/2016
1	OxazolesIBA 10/2014
1	7a- (4- (heptyloxy)phenethyl)tetrahydro- 1H- oxazolo(3,4- c)oxazoleIBA 10/2014

Therapy/Procedure

8	Therapeutics 01/2022 - 01/2008
1	Immunomodulation 01/2022